Synthesis and evaluation of triazole-linked poly(ε-caprolactone)-graft-poly(2-methyl-2-oxazoline) copolymers as potential drug carriers.

نویسندگان

  • Brieuc Guillerm
  • Vincent Darcos
  • Vincent Lapinte
  • Sophie Monge
  • Jean Coudane
  • Jean-Jacques Robin
چکیده

Well-defined graft copolymers were obtained using a copper-catalysed azide-alkyne Huisgen's cycloaddition click reaction from both biocompatible and non-toxic poly(ε-caprolactone) and poly(2-methyl-2-oxazoline) homopolymers. Resulting amphiphilic copolymers proved to form micelles that could be used as potential drug carriers.

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عنوان ژورنال:
  • Chemical communications

دوره 48 23  شماره 

صفحات  -

تاریخ انتشار 2012